Spectrophotometric thermodynamic agglomeration analysis of plant-based ingredients
Indications:
Qualitative and quantitative ingredient screening during analytical and toxicological development aimed at determining speed and size of the possible formation of primary and/or secondary ingredient aggregates and their reversibility (dissolution kinetics) or irreversibility (precipitate kinetics)
Anti-counterfeiting ingredient profiling including quantitative ingredient interaction potential profiling
Stability testing and QC – lot-to-lot consistency testing
Pre-formulation development identifying potential structural ingredient specific impurities
Optimization and planning of manufacturing processes
References:
Tahhan I, Blattert Ch, Jurischka R, Schoth A, Kerth P, Reinecke H Mechanical sealing of microfluidic structures 4M Multi-Material Micro Manufacture (Eds. Menz W, Dimov S; Elsevier Ltd.) 2005: 409 – 412
Abrahamsson B et al. A novel in vitro and numerical analysis of shear-induced drug release from extended-release tablets in the fed stomach Pharm Res 2005; (22) 8: 1215 – 1226 doi:10.1007/s11096-005-5272-x
Kucher M Particle generation during precipitative crystallization Chemie Ingenieur Technik (Eds. Wiley & Sons) 2007; (79) 3: 266 - 271
